Not a fan of how I'm pretty much not allowed to used the Super-key (Windows key) for pretty much any shortcut on 11.04. Gnome-Do is almost rendered worthless, feels like exercise doing the new keyboard shortcut I had to assign for it (Cntrl+~).
Tomboy has pretty much fallen along the way as well. What a shame, I love Tomboy Notes so much. Using a combination of Zim and Glippy Snippets for what Tomboy had been used for.
Also possibly the biggest downside is not being able to have RedShift run at start-up as well. I can get it to work manually at the terminal but I cannot get it to run at Startup, by any means possible!
Unity proving to be more pain that gain thus far.